The RAB8A Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to c-mel, RAB8, and RAB8A. This antibody recognizes Human antigen. The RAB8A Antibody has been validated for the following applications: ELISA, Flow Cytometry, Immunohistochemistry, and Western Blot.
Description
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. Anessential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. RAB8A is a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome